Medications That May Impact DAO Activity
Supporting Clinical Interpretation of the Histamine Clearance Index™
Diamine oxidase (DAO) is the primary enzyme responsible for breaking down exogenous histamine and may be inhibited by certain medications. It is important to document relevant medication use when interpreting the Histamine Clearance Index (HCI).
Decisions regarding whether to discontinue medications prior to testing should be made at the provider’s discretion.
Medications That May Impact Diamine Oxidase (DAO) and /or Histamine1
Histamine Clearance Index
The Histamine Clearance Index is a histamine intolerance test that evaluates the body’s ability to break down and eliminate histamine.
This test helps practitioners assess impaired histamine clearance associated with reduced or inhibited DAO activity, supporting clinical evaluation in patients with multisystem or allergy-like symptoms.
Diagnostic Solutions Laboratory
Brought to you by the Diagnostic Solutions Laboratory team. Our commitment is to serve the clinical needs of the health care provider with cutting-edge laboratory medicine by utilizing proven methodologies that are accurate and reliable.
The opinions expressed in this presentation are the author's own. Information is provided for informational purposes only and is not meant to be a substitute for personal advice provided by a doctor or other qualified health care professional. Patients should not use the information contained herein for diagnosing a health or fitness problem or disease. Patients should always consult with a doctor or other health care professional for medical advice or information about diagnosis and treatment.
References
- Schnedl WJ, Enko D. Histamine Intolerance Originates in the Gut. Nutrients. 2021;13(4):1262. Published 2021 Apr 12. doi:10.3390/nu13041262