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Cytokine Response Profile


Alterations in the immune system that result in chronic inflammation and autoimmunity have been linked to a wide range of health conditions and diseases. Cytokines are important mediators of many immune responses, and imbalances in cytokines have been shown to play key roles on chronic inflammation and autoimmunity.

Most cytokines can be generally characterized as pro-inflammatory or anti-inflammatory, depending on their primary effects on immune responses. Immune responses are often further characterized by the type of T helper (Th) cell involved.


CytoDx® Panel Enables Practitioners to Assess Systemic Immune Status:

  • Pro-inflammatory / anti-inflammatory cytokine balance
  • Th1, Th2, Th17 and T-regulatory cytokine responses
  • Efficacy of immune balancing and modulating approaches


CytoDx Analytes


  • GM-CSF
  • IFN gamma : Th1
  • IL-1 beta
  • IL-2 : Th1
  • IL-6
  • IL-7
  • IL-8
  • IL-12 p70 : Th1
  • IL-17A : Th17
  • IL-18
  • TNF alpha
  • IL-15
  • MIP-1 beta (CCL4)


  • IL-4 : Th2
  • IL-5 : Th2
  • IL-10 : Treg
  • IL-13 : Th2

Gut-Immune Connection

"It is now widely recognized that the gut – and especially the gut microbiome – plays a critical role in regulating immune function, and has been shown to affect circulating cytokines such IL-6, TNF-alpha, and IL-17."






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Empowering New Clinical Insights

Once again, Diagnostic Solutions Laboratory is on the forefront of laboratory science, bringing clinicians the latest revolutionary clinical assessment tool, the CytoDx®.

With an assessment of 18 cytokines, the CytoDx® provides clinicians with powerful insight into their patient's systemic immune regulatory function, allowing for advanced health assessment and individualized treatment plans based on specific immune responses.


Services provided are for laboratory testing only. No charge is incurred for ordering collection kits.



Specimen Requirements

Single serum collection shipped frozen on dry ice.


Collection Kit Contents

Test kits include specimen collection instructions, test request form, SST tube, specimen bag, Ice Pack, pre-paid Clinical Pak mailer.


Test Turnaround Time

7–10 business days days


Getting Started

Account setup forms are available here, or by phone at 877-485-5336


Sample Report

Product Brief


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