Educational Articles
Common Gene Variant Predisposes to Irritable Bowel Syndrome
Implications for Precision Therapies
Overview
The small intestinal brush border enzyme sucrase-isomaltase (SI) plays a critical role in carbohydrate digestion
A common variant in the gene encoding SI was shown to be strongly associated with an increased risk of IBS
The SI gene variant was shown... read more »
Understanding Calprotectin and Lab-Specific Reference Ranges
by Heather Vatter, PhD
What is Calprotectin?
Calprotectin is a 36 kDa heterodimeric calcium bind protein that comprises approximately 60% of the cytosolic proteins present in inflammatory cells. Therefore, during intestinal inflammation, calprotectin quantification can be used to measure the... read more »
The GI-MAP™ in Clinical Practice
Last summer, two different boys, a ten-year-old and a seventeen-year-old, presented to my clinic with similar GI complaints. The families were unrelated and located in different areas, but both boys had symptoms of nausea, vomiting, and heartburn that were accompanied by poor reactions to certain... read more »